For me, it would be GLaDOS.
Portal 2 spoiler
She deleted the one remaining human part of herself because it was just too much to deal with. She releases you at the end of Portal 2 as a path of least resistance measure because “killing you is hard.”
What about you, what is your favorite media villain?


Naraku, hes basically a troll that is also malevolent, oddly although he despises humans most of his goals dont harm them directly through out the series until the very end when hes get desperate, as he never targets humans directly unlike most other demons, or his own incarnation which he ends up killing to prevent them from interfering. or if you want to dig a little deeper, the shikon jewel is an amoral villian, sacrifices any user who made wishes to keep itself alive. hes a complex characther, he has much more contempt for demons than humans, eventhough he hates humans, but has not alright vindictiveness like he has against inuyash and his gang going on unless they gets in his way.