cross-posted from: https://lemmy.blahaj.zone/post/42741188

James Walker, a professor emeritus of obstetrics and gynaecology at the University of Leeds, said the research had helped to “cut through the noise” regarding recent concerns regarding whether medications taken by mothers during pregnancy could affect their babies.

“The practical message is straightforward” Walker said. “Women with moderate or severe depression should not stop their antidepressants in pregnancy out of fear of causing autism or ADHD. Depression that goes untreated in pregnancy carries real risks of its own, for the mother, the pregnancy and for the developing baby, including a higher chance of premature birth, postnatal depression and difficulties bonding with the baby. For milder depression, talking therapies and other non-medication approaches are usually tried first, in line with current guidelines. As always, decisions in pregnancy are personal and should be made with a clinician who knows the woman’s history.”

  • otacon239@lemmy.world
    link
    fedilink
    English
    arrow-up
    25
    ·
    2 days ago

    Have we even found a single link between habits/conditions of pregnancy and ADHD/autism yet? I feel like every time I hear these stories, it’s a repeat of the last study’s findings.

    • No_Eponym@lemmy.ca
      link
      fedilink
      English
      arrow-up
      5
      ·
      2 days ago

      A substantial body of evidence links maternal infection during pregnancy to adverse neurodevelopmental outcomes in offspring. Large national registry studies have reported increased risks of neuropsychiatric disease such as autism spectrum disorder, cognitive delay, schizophrenia, and mood disorders after in utero exposure to maternal infections.

      Links: https://journals.lww.com/greenjournal/fulltext/2026/01000/neurodevelopmental_outcomes_of_3_year_old_children.4.aspx

      https://pubmed.ncbi.nlm.nih.gov/27287966/

    • Lost_My_Mind@lemmy.world
      link
      fedilink
      English
      arrow-up
      9
      arrow-down
      1
      ·
      2 days ago

      I want to see a modern study on cigerette smoking.

      When I was a kid (early 90s), my mom defended her decision to not stop smoking when she was pregnant with me, by quoting a study from the 1970s. They found it did not cause any ill effects.

      Well around 2005 I was poking around the internet, and found that yes, that study was reported exactly how she claimed, and was performed by the Nixon administration.

      It was also funded by Marlborrow. So take that study with a salt mine worth of salt.

      I want a new modern independant study done. Because my mom never stopped, and I have always felt like something is wrong with me, but I’m too dumb to put it into words. I’m not calling it autism, but it feels like there’s a mental blockade preventing me from being me. I don’t know how to explain it.

      • velma@lemmy.blahaj.zoneOP
        link
        fedilink
        English
        arrow-up
        6
        ·
        edit-2
        2 days ago

        There’s general risk with some foods as well, like raw seafood/meat, seafood high in mercury, and unpasteurized dairy.

    • velma@lemmy.blahaj.zoneOP
      link
      fedilink
      English
      arrow-up
      2
      ·
      2 days ago

      It’s pretty obvious that there’s a hereditary component to ADHD/autism. But it’s one of those things that needs further study to prove and since it’s difficult to test these medications on pregnant women, it takes longer.

    • Buffalox@lemmy.world
      link
      fedilink
      English
      arrow-up
      1
      arrow-down
      7
      ·
      2 days ago

      This one is a meta study based on other studies, so I guess that’s to be expected.
      Everything is a fucking meta study today, and IMO they are too often shit, because they generally try to account for variables that the original studies weren’t made for.
      Ah well, it’s probably going to get worse, because now we will be overwhelmed by meta studies that are made by AI.

      • Aatube@lemmy.dbzer0.com
        link
        fedilink
        English
        arrow-up
        10
        ·
        2 days ago

        meta studies are the highest standard of evidence. when peer-reviewed, looking at old evidence in new lights is precisely what they’re supposed to do, and there’s no problem with that unless there’s a response/refutal along those lines.

        i haven’t seen them be at a higher frequency than usual either; in fact the latest data i could find shows it’s slowed down since 2019: https://pmc.ncbi.nlm.nih.gov/articles/PMC11795965/figure/cesm70010-fig-0002/ (note that the data cutoff is May 2024)

        because now we will be overwhelmed by meta studies that are made by AI.

        Have we even found a single major-journal systematic review that was made by AI yet?

      • CyberEgg@discuss.tchncs.de
        link
        fedilink
        English
        arrow-up
        7
        ·
        2 days ago

        Do you even know what a meta study is? It is not just “this amount of research says this and this amount of research says that”, the actually important and actual work that goes into a meta study is to point out weaknesses of the examined base studies to weigh their informative value on the meta study’s topic.

      • stoly@lemmy.world
        link
        fedilink
        English
        arrow-up
        3
        ·
        2 days ago

        It’s sad that you feel so strongly about it but won’t take the time to learn how these things work.

    • FinjaminPoach@lemmy.world
      link
      fedilink
      English
      arrow-up
      1
      arrow-down
      6
      ·
      2 days ago

      Yes - I’ve heard that women with autism are more likely to experience pains in pregnancy and thus choose to use painkiller (e.g Tylenol or another brand of paracetamol). Autism being sometimes inherited, there is then a correlation if you study it.

      This sounded weird to me, but I also have heard women who give birth at a later age are more likely to have a child with autism. Maybe older pregnant women will have more pain during pregnancy? In which case there should be a correlation between painkillers usage while pregnant, and autism rates in offspring.

      • stoly@lemmy.world
        link
        fedilink
        English
        arrow-up
        2
        ·
        2 days ago

        People with autism also tend to be more sensitive to physical stimulus of any sort and so may more acutely experience bodily sensations.

      • velma@lemmy.blahaj.zoneOP
        link
        fedilink
        English
        arrow-up
        1
        ·
        2 days ago

        There is a correlation, which is why the Trump administration was pushing the dangerous idea that pregnant women should not use acetaminophen because it will give their children autism. It’s not a causation though.

        Pregnant women are limited to only acetaminophen for reducing fevers and treating pain.

        • FinjaminPoach@lemmy.world
          link
          fedilink
          English
          arrow-up
          1
          arrow-down
          1
          ·
          2 days ago

          It’s not a causation though

          Yep, that’s precisely what i was trying to say.

          Pregnant women are limited to only acetaminophen for reducing fevers and treating pain.

          Oh okay, that’s weird because i thought the whole debate was about one specific painkiller that i remembered began with T.

          • velma@lemmy.blahaj.zoneOP
            link
            fedilink
            English
            arrow-up
            2
            ·
            2 days ago

            I was agreeing with you :)

            Tylenol is the brand name in the US for acetaminophen. It’s the same as paracetamol. It’s the only fever reducer and pain reliever pregnant women can take.